Collagen Biostimulator: Marylebone

JULÄINE™

JULÄINE™ is an advanced collagen-stimulating injectable (biostimulator) that rejuvenates the skin from within by encouraging the body to rebuild its own collagen and elastin.

JULÄINE collagen biostimulator treatment with Dr Paul Elgey at UNTIL Marylebone
Skin firmness and radiance restored with JULÄINE collagen biostimulator

Regenerative treatment

JULÄINE™ Collagen Biostimulator in London

JULÄINE™ is an advanced collagen-stimulating injectable (biostimulator) that rejuvenates the skin from within by encouraging the body to rebuild its own collagen and elastin.

Unlike dermal fillers, which create instant volume, JULÄINE™ works gradually and naturally to restore the skin's structure, firmness, and radiance.

For patients seeking subtle, long-lasting improvement without looking done, JULÄINE™ represents a new standard in regenerative aesthetics. By enhancing skin quality over time, it leaves you looking fresher, healthier, and more confident.

At my Marylebone clinic I specialise in bespoke, natural results. JULÄINE™ fits seamlessly into that philosophy.

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  • Medical Expertise

    Over 20 years of medical experience, specialising in natural full-face rejuvenation.

  • Safety First

    Treatments performed by a GMC-registered doctor, with advanced training in facial anatomy and complication management.

  • Bespoke Approach

    Every treatment plan is tailored to your facial structure, goals, and skin health.

  • Natural Philosophy

    Focus on subtle, undetectable results that enhance rather than alter.

5.0 out of 5

Based on 72 Google reviews

Read our reviews on Google

So happy to have found Dr Paul. I originally went in wanting a specific treatment but once Dr Paul explained my facial structure we went for a different plan and I couldn’t be happier with the results. He has a true eye for natural aesthetics. He’s also lovely and has an amazing clinic space.

Open Mindeda year ago
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I had a great experience with Paul for lip filler and Sunekos injections. He is attentive, friendly, and very knowledgeable. He took the time to understand my facial structure, how it moved to ensure a nice balanced and natural look. Also appreciate that he isn’t afraid to say no to more treatments so that things don’t look overdone. Will always be happy to recommend!

Aliesha Kumar1 month ago
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I have been seeing Dr. Paul for over 3/4 years for a combination of treatments and I couldn’t be happier with the results. His professionalism and meticulous attention to detail are second to none — he truly is a perfectionist in his work. He always takes the time to listen, explain the procedure, and ensure I feel comfortable. I highly recommend Dr. Paul to anyone considering aesthetic treatments — his ability to deliver natural enhancements is truly outstanding.

Filiz2 months ago
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Dr Paul has been my esthetician for more than 7 years now and honestly it was worth flying to London just for his treatments. He is a brilliant doctor with a great sense of esthetics. Every treatment I did with him was well measured, explained and executed. He takes his time to explain which treatments are beneficial now, and which treatments I should be thinking about for upcoming future. Planning is key! One of his advantages is his quick and light hand technique that personally for me leaves no bruises.

Maria Ivv11 months ago
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I went to Dr Elgey and had 4 mls of dermal filler which he strategically placed in the temples, cheeks and chin and I am honestly blown away by the results. It’s a real game changer! I went in feeling super nervous but Dr Elgey is so knowledgeable, professional and warm - I quickly felt at ease. We spoke at length about my concerns and then he advised me on where the filler should be placed to get the best results. I had absolutely no bruising afterwards and swelling was minimal. The result is so natural but I look so much younger and fresher. I honestly wish I had done it sooner.

Janet Thompson1 year ago
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Paul is fantastic. He uses his experience to understand what you’re looking for and advise on what may work, he does not push or upsell any treatments and he has a real creativity and specialises in achieving a natural result. I trust his knowledge and skills, and his ethics.

Sally Tucker10 months ago
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I have had my lip filler done a few times with Paul and they are perfect every time. A natural and full look that I get so many compliments on. Always a lush experience, I highly recommend!

Lily7 months ago
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I had a consultation and UltraClear treatment with Dr Paul for acne scarring with other skin concerns and my experience has been excellent from start to finish. After speaking with several practitioners, what stood out most was Dr Paul’s honesty and knowledge. I never felt pressured into treatment, and he took the time to explain the reasoning behind his recommendations. Throughout the process, he has been incredibly responsive and supportive, answering all of my questions before and after treatment. He also prepared a personalised pre-treatment skincare cream which made me feel very well looked after. The recovery has also gone smoothly thanks to the clear aftercare instructions and Dr Paul’s ongoing support.

Arya Erkılınçoğlu3 weeks ago
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Dr Paul Elgey delivering an injectable treatment at his Marylebone clinic

The treatment

What is JULÄINE™?

JULÄINE™ is an advanced collagen-stimulating injectable, a biostimulator based on poly-L-lactic acid (PLLA) microspheres, a material used safely in medicine for decades. Rather than adding instant volume like a hyaluronic acid filler, it prompts the skin to rebuild its own collagen and elastin, so improvement develops gradually and looks like better skin rather than treated skin.

For patients seeking subtle, long-lasting improvement without looking overdone, JULÄINE™ fits our philosophy of bespoke, natural results, leaving you looking fresher, healthier, and more confident.

Book a Consultation
Skin density and texture across the neck and shoulders after treatment

Indications and applications

What Can JULÄINE™ Treat?

JULÄINE™ is particularly effective for:

Rebuild collagen and support

JULÄINE™ stimulates fibroblasts to produce new collagen, restoring your own structural support rather than adding volume.

Restore firmness and density

Over the following months it improves skin firmness, density, texture and radiance.

Refine the jawline and lower face

It sharpens definition along the jawline and chin and softens early jowling and marionette lines.

Improve skin quality gradually

Results build slowly and naturally, so there is no sudden change, just steady rejuvenation.

Treat more than the face

It also improves crepey texture and fine lines on the neck, décolletage and hands.

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What to expect during and after your session

  • Treatment time30 to 60 minutes
  • CourseTwo to three sessions
  • Results buildOver 2 to 3 months
  • Results last12 to 24 months
  • DowntimeBack to normal the same day
  • AnaestheticApplied if needed
  • Compatible withDermal Filler
Jawline and lower face definition improved with JULÄINE

Treatment areas

What Areas Can JULÄINE™ Treat?

JULÄINE™ is suitable for patients who want to improve:

  • Midface and cheeks: restoring contour and firmness
  • Jawline: sharpening definition and structure
  • Chin: improving projection and balance
  • Lower face: softening marionette lines and early jowling
  • Neck and décolletage: improving fine lines and crepey texture
  • Hands: restoring youthful density

It is not used for lip augmentation but complements other treatments beautifully when improving the overall harmony of the face.

Discuss Your Suitability Today
Neck and décolletage treated with JULÄINE collagen biostimulator

How it compares

JULÄINE vs Other Treatments

JULÄINE™ vs dermal fillers. Fillers provide instant volume and lifting. JULÄINE™ improves underlying skin quality and firmness over time. Many patients combine both: fillers for structure, JULÄINE™ for regeneration.

JULÄINE™ vs Sculptra (older PLLA). JULÄINE™ uses more uniform microspheres, reducing inflammation and the risk of nodules. There is no need for post-treatment massage, which Sculptra requires. Results are smoother and more predictable.

JULÄINE™ vs skin boosters and polynucleotides. Skin boosters improve hydration and glow. Polynucleotides repair and rejuvenate at a cellular level. JULÄINE™ works deeper, regenerating collagen networks for structural integrity.

Understand the Science Behind Treatment

What can be treated?

JULÄINE™ stimulates your own collagen to gradually rebuild firmness, density, and skin quality rather than adding instant volume.

Treatment areas

Face

  • Midface and cheeks
  • Jawline
  • Chin
  • Lower face

Body

  • Neck
  • Décolletage
  • Hands

Technique and safety

How your JULÄINE™ is delivered

JULÄINE™ uses refined, uniform PLLA microspheres placed by a GMC-registered doctor to rebuild your own collagen, so results develop gradually and look entirely natural, never overdone.

Dr Paul Elgey, aesthetic doctor, London
  • Over 20 years of medical experience, specialising in natural full-face rejuvenation
  • Performed by a GMC-registered doctor with advanced training in facial anatomy
  • Every plan is tailored to your facial structure, goals, and skin health
  • Refined microsphere technology reduces the risk of nodules, with no post-treatment massage required
  • Results typically last 12 to 24 months and can be extended with maintenance
Improved skin density and texture across the décolletage after JULÄINE

Incredible outcomes

Benefits of JULÄINE™

  • Collagen regeneration: restores the skin's own support structure.
  • Natural results: no sudden changes, just gradual rejuvenation.
  • Improved skin quality: enhanced firmness, density, texture and radiance.
  • Long lasting effects: results can last 12 to 24 months or more.
  • Low maintenance: fewer top-ups compared to some fillers or skin boosters.
  • Versatile use: effective for midface, jawline, chin, perioral region, neck, décolletage, and hands.
  • Safer than older PLLA injectables: refined microsphere technology reduces the risk of nodules and means massage is no longer required after treatment.
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Dr Paul Elgey treating a patient at his Marylebone clinic

Your treatment journey

What to Expect

Your JULÄINE™ journey is personalised to your goals.

We begin with a detailed facial analysis, reviewing your skin health, history, and treatment goals. Every plan is bespoke, ensuring results that enhance your natural features.

The procedure usually takes 30 to 60 minutes. After cleansing and applying anaesthetic if needed, small amounts of JULÄINE™ are carefully injected into targeted areas. You may experience mild redness, swelling, or bruising, which typically resolves within 1 to 3 days, and most patients return to normal activities the same day.

Unlike fillers, results are not instant. Improvements appear gradually over 2 to 3 months as new collagen forms, with full results developing after completing the treatment course. Effects typically last 12 to 24 months, with some patients enjoying benefits for up to 3 years. Maintenance sessions can extend results.

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Pricing

JULÄINE™ Pricing

Pricing depends on:

  • The number of vials needed for the areas treated
  • Whether one region or several are being regenerated
  • The number of sessions in your course

JULÄINE is a course treatment that builds over months, so you are quoted for the plan rather than the appointment. That happens at consultation, before anything is booked.

Book a Consultation for a Personalised Quote
Dr Paul Elgey in consultation with a patient at his Marylebone clinic

Doctor-led biostimulation

Why Choose Dr Paul Elgey?

A biostimulator asks you to trust a result you cannot see for two to three months. That trust has to be earned at the consultation, with an honest account of what will change and when.

With over 20 years of medical practice and advanced aesthetic training, my focus is:

  • Safety
  • Precision
  • Natural outcomes
  • Long-term skin health

JULÄINE is not the answer for everyone. If filler or a skin booster would serve you better, that is what I will recommend.

Book a JULÄINE Appointment with Dr Paul

Book a Consultation

A doctor-led consultation focused on natural, balanced results. Share your goals and concerns and we will guide you through the most appropriate treatment plan.

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JULÄINE™ FAQs

If you are curious about the treatment, the timeline, or how JULÄINE™ compares to other options, the answers to common questions are below. Biostimulators work gradually, so expectations matter as much as technique.

What makes JULÄINE™ different from dermal fillers?

Dermal fillers provide instant volume. JULÄINE™ stimulates your skin’s own collagen, gradually improving firmness, density, and texture over time.

How does JULÄINE™ work?

JULÄINE™ is powered by poly-L-lactic acid (PLLA) microspheres, a clinically proven material used safely in medicine for decades. Its formulation is designed to trigger the skin’s natural healing and regenerative pathways, resulting in the production of new collagen fibres. Injection: Tiny, uniform PLLA microspheres are injected into targeted areas of the skin using a cannula. Stimulation: Fibroblasts (skin cells responsible for collagen production) are activated, producing new type I and type III collagen. Regeneration: Over weeks and months, collagen networks rebuild skin thickness, resilience, and elasticity. Absorption: The PLLA is gradually broken down and absorbed by the body, leaving only your natural collagen behind. This slow and steady process avoids the “sudden change” that some patients worry about with dermal fillers. Instead, improvements unfold gradually, making JULÄINE™ ideal for patients who want natural-looking anti-ageing results.

How many treatments will I need?

Most patients need 2–3 sessions, spaced 3–6 weeks apart, for best results.

When will I see results?

Subtle improvements may be noticed within weeks, but the most significant changes develop after 2–3 months.

How long do results last?

On average 12–24 months, with many patients reporting results lasting up to 3 years.

Is JULÄINE safe?

Yes, when administered by a qualified medical professional. It has a strong safety record and is CE-marked in Europe.

Is the treatment painful?

Discomfort is usually minimal. JULÄINE™ is delivered through a fine cannula rather than multiple needle points, and I apply topical anaesthetic where needed to keep you comfortable. Most patients describe the sensation as mild pressure rather than pain, and any tenderness settles within a day or two.

What is the downtime?

Most patients resume daily activities immediately. Temporary swelling or bruising may last a few days.

Are there any risks?

JULÄINE™ has an excellent safety profile when performed by an experienced medical professional. Common side effects Mild redness Swelling Bruising Tenderness These usually resolve within a few days. Less common risks Small nodules or irregularities (rare with JULÄINE™ due to its refined formulation). Vascular complications if injected incorrectly – another reason to choose a highly trained medical doctor. Contraindications Pregnancy or breastfeeding Active skin infection Autoimmune conditions or bleeding disorders Allergy to any component Your consultation will include a full medical history to ensure you are a safe and suitable candidate.

Can it be combined with other treatments?

Yes. Many patients benefit from combining JULÄINE™ with fillers, skin boosters, or polynucleotides for a layered approach to rejuvenation.

Who should avoid JULÄINE™?

Those who are pregnant, breastfeeding, or with certain medical conditions may not be suitable. This will be fully discussed in consultation.

Written and medically reviewed byDr Paul Elgey, Aesthetic Doctor & GP: MBBS MRCGP · MHRA (Medicines and Healthcare products Regulatory Agency): poly-L-lactic acid collagen biostimulators are CE-marked medical devices.

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Dr Paul Elgey Aesthetics • UNTIL Marylebone, 1 Orchard Street, London W1H 6HJ

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Appointments typically available within 1–2 weeks